Mild Cognitive Impairment (MCI) is an early stage preceding dementia, common among the elderly. Undetected MCI significantly reduces quality of life and increases healthcare burdens. As global societies age, cognitive decline prevalence rises, creating public health challenges. Conventional tools like the Mini-Mental State Examination and Montreal Cognitive Assessment (MoCA) require trained professionals and extended time, limiting suitability for large-scale, home-based screening. To address these limitations, this project presents MindZone, an intelligent game-based platform for cognitive screening and cognitive-motor training. Designed for home use, MindZone allows caregivers and professionals to monitor performance remotely. The platform integrates interactive brain training, a handheld grip-based motion detection device, and artificial intelligence, including image classification for drawing tasks and voice recognition for language responses, to analyze data in real time. The system comprises two main components: a digital cognitive assessment adapted from the MoCA framework to identify MCI risks, and a cognitive-motor training system combining physical movement with structured cognitive tasks to enhance executive functions and cognitive reserve. Cognitive training is delivered through three engaging games: MindGarden, which promotes planning, memory recall, and task sequencing through virtual plant cultivation; Meteor Blaster, which requires striking motions to destroy meteors, training reaction speed, bilateral coordination, and left-right neural separation; and RapidRaft, involving rhythmic rowing to avoid obstacles, promoting hand-eye coordination and spatial awareness. MindZone was evaluated with 42 participants aged 50 to 70 through pilot testing, controlled testing, and three months of continuous real-world home use. Results demonstrated significant improvements in physical performance, cognitive functions, and user satisfaction. These findings indicate strong potential for accessible early MCI screening and caregiver-supported monitoring. By combining AI-driven assessment with physical interaction, MindZone offers a scalable solution for long-term physical and mental well-being in the elderly, bridging the gap between clinical evaluation and daily home care. This integrated approach ensures that cognitive health management becomes more proactive, engaging, and accessible for the growing aging population, ultimately reducing the overall socioeconomic impact of cognitive decline worldwide.